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Article

Polymorphisms in Sex Hormone Metabolism Genes and Risk of Preeclampsia in Taiyuan, China.

Gynecologic and obstetric investigation - 1 Jan 2018

Zhang Ping, Yang Hailan, Feng Yongliang, Wu Weiwei, Li Shuzhen, Thompson Brian, Xie Bingjie, Guo Pengge, Li Mei, Wang Ying, Zhao Nan, Wang Suping, Zhang Yawei

Abstract excerpt

OBJECTIVE: Aberrant synthesis and metabolism of sex hormone are likely to be associated with alterations in vascular function in preeclampsia (PE). The study aims to investigate whether single nucleotide polymorphisms (SNPs) in sex hormone-related genes are associated with PE. METHOD: We performed a nested case-control study including 436 pregnant women (203 PE and 233 healthy or normal pregnant women) to...

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Source

Identifiers

PMID: 29059671
DOI: 10.1159/000478931

Genes

COMT
GNRHR
LHCGR
SULF1
TXNRD2

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