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Article

Haplotype-based case-control study of estrogen receptor alpha (ESR1) gene and pregnancy-induced hypertension.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Feb 2008

Tamura Masaaki, Nakayama Tomohiro, Sato Ichiro, Sato Naoyuki, Izawa Noriko, Hishiki Mikano, Mizutani Yoshihiro, Furuya Kiyohide, Yamamoto Tatsuo

Abstract excerpt

Hypotheses about pregnancy-induced hypertension (PIH) have been proposed to explain the vascular damage that characterizes this disease. Reports indicate that estrogens and estrogen receptors play important physiological roles in cardiovascular diseases. There have been studies examining the association between coronary artery disease and the estrogen receptor alpha (ESR1) gene. The aim of the present work was to...

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Source

Identifiers

PMID: 18360040
DOI: 10.1291/hypres.31.221

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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