Article
Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility.
Carcinogenesis - 1 Aug 2012
Wei Sheng, Wang Li-E, McHugh Michelle K, Han Younghun, Xiong Momiao, Amos Christopher I, Spitz Margaret R, Wei Qingyi Wei
Abstract excerpt
Asbestos exposure is a known risk factor for lung cancer. Although recent genome-wide association studies (GWASs) have identified some novel loci for lung cancer risk, few addressed genome-wide gene-environment interactions. To determine gene-asbestos interactions in lung cancer risk, we conducted genome-wide gene-environment interaction analyses at levels of single nucleotide polymorphisms (SNPs), genes and...
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