Article
Genome-wide Gene-Asbestos Exposure Interaction Association Study Identifies a Common Susceptibility Variant on 22q13.31 Associated with Lung Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2015
Liu Chen-Yu, Stücker Isabelle, Chen Chu, Goodman Gary, McHugh Michelle K, D'Amelio Anthony M, Etzel Carol J, Li Su, Lin Xihong, Christiani David C
Abstract excerpt
BACKGROUND: Occupational asbestos exposure has been found to increase lung cancer risk in epidemiologic studies. METHODS: We conducted an asbestos exposure-gene interaction analyses among several Caucasian populations who were current or ex-smokers. The discovery phase included 833 Caucasian cases and 739 Caucasian controls, and used a genome-wide association study (GWAS) to identify single-nucleotide...
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