Article
Genetic variation in innate immunity and inflammation pathways associated with lung cancer risk.
Cancer - 15 Nov 2012
Shiels Meredith S, Engels Eric A, Shi Jianxin, Landi Maria Teresa, Albanes Demetrius, Chatterjee Nilanjan, Chanock Stephen J, Caporaso Neil E, Chaturvedi Anil K
Abstract excerpt
BACKGROUND: Pulmonary inflammation may contribute to lung cancer etiology. The authors conducted a broad evaluation of the association of single nucleotide polymorphisms (SNPs) in innate immunity and inflammation pathways with lung cancer risk and conducted comparisons with a lung cancer genome-wide association study (GWAS). METHODS: In total, 378 patients with lung cancer (cases) and a group of 450 controls from...
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