Article
Molecular and genetic changes in asbestos-related lung cancer.
Cancer letters - 28 Jun 2008
Nymark Penny, Wikman Harriet, Hienonen-Kempas Tuija, Anttila Sisko
Abstract excerpt
Asbestos-exposure is associated with an increased risk of lung cancer, one of the leading causes of cancer deaths worldwide. Asbestos is known to induce DNA and chromosomal damage as well as aberrations in signalling pathways, such as the MAPK and NF-kappaB cascades, crucial for cellular homeosta...
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