Article
Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors.
Journal of hepatology - 1 Oct 2012
Huang Cheng-Hao, Yuan Quan, Chen Pei-Jer, Zhang Ya-Li, Chen Chang-Rong, Zheng Qing-Bing, Yeh Shiou-Hwei, Yu Hai, Xue Yu, Chen Yi-Xin, Liu Ping-Guo, Ge Sheng-Xiang, Zhang Jun, Xia Ning-Shao
Abstract excerpt
BACKGROUND & AIMS: This study aimed at investigating mutations in the hepatitis B surface protein (HBsAg) in occult hepatitis B virus (HBV) infection (OBI) and their influence on viral antigenicity and phenotype. METHODS: The characteristics of 61 carriers with OBI (OBI group), 153 HBsAg(+) carriers with serum HBsAg ≤ 100 IU/ml (HBsAg-L group) and 54 carriers with serum HBsAg >100 IU/ml (HBsAg-H group) from...
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