Article
Unique surface gene variants of hepatitis B virus isolated from patients in the Philippines.
Journal of medical virology - 1 Feb 2014
Baclig Michael O, Alvarez May R, Gopez-Cervantes Juliet, Natividad Filipinas F
Abstract excerpt
Point mutations and multiple variants across the "a" determinant can destroy the antigenicity and immunogenicity of hepatitis B virus (HBV) leading to false negative assay and vaccine escape. In this study, the presence of surface gene variants of HBV was investigated among patients clinically diagnosed with chronic hepatitis B and positive for HBV DNA from 2002 to 2009. Sequence analysis of the surface gene of...
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