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Article

Impact of hepatitis B virus surface protein mutations on the diagnosis of occult hepatitis B virus infection.

Hepatology (Baltimore, Md.) - 1 Nov 2010

El Chaar Mira, Candotti Daniel, Crowther R Anthony, Allain Jean Pierre

Abstract excerpt

UNLABELLED: Genotype D occult hepatitis B virus (HBV) infections (OBIs) have a high frequency of amino acid substitutions in the major hydrophilic region of the small surface protein (S protein). This possibly reflects an escape mutation mechanism to evade detection by the host immune system. Mutations may also impact the detection of hepatitis B surface antigen (HBsAg) by commercial assays. To test these...

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Identifiers

PMID: 20815025
DOI: 10.1002/hep.23886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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