Article
Association study of polymorphisms in the cyclooxygenase-2 gene and Alzheimer's disease risk in Chinese.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 May 2013
Tang Wenlu, He Meixia, Yang Bo, Wei Kankan, Yin Ming, Zhang Lirong
Abstract excerpt
To determine if polymorphisms (-765G/C, -1195G/A and 8473T/C) of the cyclooxygenase-2 (COX-2) gene can be associated with Alzheimer disease (AD). The frequency of the polymorphisms was determined in 244 cases and 226 controls. The results revealed that the distributions of COX-2 -765G/C and 8473T/C polymorphisms were statistically not significant between AD cases and controls. The genotype distributions and...
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