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Article

Influence of the Cyclooxygenase-2 Gene -765G/C and -1195G/A Polymorphisms on Development of Ischemic Stroke.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Sept 2016

Wu Guangliang, Cai Haiyan, Cai Haobin, Chen Zhao, Tan Lei, Qin Xiurong, Cai Yefeng

Abstract excerpt

BACKGROUND: Many studies have investigated the association between the cyclooxygenase-2 (COX-2) gene polymorphism and ischemic stroke. However, results of these studies still remain controversial. To better explain the association between COX-2 polymorphisms (-765G/C and -1195G/A) and ischemic stroke risk, a meta-analysis was performed. METHODS: Relevant studies were identified from 4 Chinese databases (Chinese...

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PMID: 27363623
DOI: 10.1016/j.jstrokecerebrovasdis.2016.06.001

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