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Article

Cyclooxygenase-2 genetic polymorphism and stroke subtypes in Chinese.

Journal of molecular neuroscience : MN - 1 Oct 2013

Chen Guo-zhong, Shan Xiao-yun, Cheng Gan-ping, Tao Hong-miao

Abstract excerpt

BACKGROUND: Cyclooxygenase-2 (COX-2) catalyzes the formation of prostaglandins that contribute to the inflammation in atherosclerosis. The aim of the present study was to investigate the relationship between two polymorphisms (-1195G>A and -765G>C) in the COX-2 gene and subtypes of ischemic stroke in a Chinese population. METHODS: Genomic DNA of 224 patients with large artery atherosclerosis (LAA), 329 patients...

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PMID: 23907768
DOI: 10.1007/s12031-013-0078-5

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