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Article

The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease.

Neuroscience letters - 13 Mar 2006

Abdullah Laila, Ait-Ghezala Ghania, Crawford Fiona, Crowell Timothy A, Barker Warren W, Duara Ranjan, Mullan Michael

Abstract excerpt

The cyclooxygenase-2 enzyme (COX-2) is of particular importance in the inflammatory response and recent findings have demonstrated a considerable role in Alzheimer's disease (AD) pathogenesis. In order to assess the possible putative role of a COX-2 polymorphism (765G/C) in AD, we examined its distribution in 161 community-based controls and 168 AD clinic-based cases previously recruited from memory disorder...

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Identifiers

PMID: 16309832
DOI: 10.1016/j.neulet.2005.10.090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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