Article
Association of the cyclooxygenase-2 1759A allele with migraine in Chinese Han individuals.
PloS one - 1 Jan 2020
Guan Xinying, Dong Changhong, Zhu Pinhuan, Chen Cheng, Wang Teng, Wu Mengping, Dong Xin
Abstract excerpt
Cyclooxygenase-2 (COX-2) is known to be involved in the pathogenesis of migraine, and some polymorphisms are known to affect the expression of COX-2. This retrospective case-control study aimed to explore the associations between the -765 G>C (rs20417), -1759 G>A (rs3218625), and -8473 C>T (rs5275) COX-2 polymorphisms and migraine in Chinese Han individuals. One hundred and ten unrelated Han Chinese patients with...
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