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Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice.

Hepatology (Baltimore, Md.) - 1 Nov 2012

Höchst Bastian, Schildberg Frank A, Böttcher Jan, Metzger Christina, Huss Sebastian, Türler Andreas, Overhaus Markus, Knoblich Andreas, Schneider Berthold, Pantelis Dimitrios, Kurts Christian, Kalff Jörg C, Knolle Percy, Diehl Linda

Abstract excerpt

UNLABELLED: Immunity against cancer is impeded by local mechanisms promoting development of tumor-specific T cell tolerance, such as regulatory T cells, myeloid-derived suppressor cells, or immunosuppressive factors in the tumor microenvironment. The release of soluble antigens, such as carcinoembryonic antigen (CEA) from colorectal carcinoma (CRC) cells, has been investigated for diagnostic purposes, but not for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22610745
DOI: 10.1002/hep.25844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice.PMID 22610745Read ↗

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