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Article

Integrating Genetics and Environment to Find Causal Mechanisms for Multiple Sclerosis.

European journal of immunology - 1 May 2026

Leon Alicia Munoz, Lincoln Matthew R

Abstract excerpt

Genome-wide association studies (GWAS) have identified hundreds of risk loci for multiple sclerosis (MS), but we have limited knowledge of the mechanisms through which genetic variants mediate risk. Similarly, epidemiological studies implicate numerous environmental risk factors in MS risk, but these cannot identify specific causal mechanisms. We review our current knowledge of genetic mechanisms in MS, including...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42125982
DOI: 10.1002/eji.70206
PMCID: PMC13169484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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