Article
INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America - 29 May 2012
Ausin Israel, Greenberg Maxim V C, Simanshu Dhirendra K, Hale Christopher J, Vashisht Ajay A, Simon Stacey A, Lee Tzuu-fen, Feng Suhua, Española Sophia D, Meyers Blake C, Wohlschlegel James A, Patel Dinshaw J, Jacobsen Steven E
Abstract excerpt
At least three pathways control maintenance of DNA cytosine methylation in Arabidopsis thaliana. However, the RNA-directed DNA methylation (RdDM) pathway is solely responsible for establishment of this silencing mark. We previously described INVOLVED IN DE NOVO 2 (IDN2) as being an RNA-binding RdDM component that is required for DNA methylation establishment. In this study, we describe the discovery of two...
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