Article
Atypical RNA polymerase subunits required for RNA-directed DNA methylation.
Nature genetics - 1 Jul 2005
Kanno Tatsuo, Huettel Bruno, Mette M Florian, Aufsatz Werner, Jaligot Estelle, Daxinger Lucia, Kreil David P, Matzke Marjori, Matzke Antonius J M
Abstract excerpt
RNA-directed DNA methylation, one of several RNA interference-mediated pathways in the nucleus, has been documented in plants and in human cells. Despite progress in identifying the DNA methyltransferases, histone-modifying enzymes and RNA interference proteins needed for RNA-directed DNA methylation, the mechanism remains incompletely understood. We screened for mutants defective in RNA-directed DNA methylation...
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