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Article

Detection of EGFR somatic mutations in non-small cell lung cancer (NSCLC) using a novel mutant-enriched liquidchip (MEL) technology.

Current drug metabolism - 1 Sept 2012

Zhang Li, Yang Huiyi, Zhao Yanwei, Liu Wenchao, Wu Shiyang, He Jiaying, Luo Xiaodi, Zhu Zeyao, Xu Jiasen, Zhou Qinghua, Ren-Heidenreich Lifen

Abstract excerpt

We have developed and standardized a novel technology, mutant-enriched liquidchip (MEL), for clinical detection of EGFR mutations. The MEL integrates a mutant-enriched PCR procedure with liquidchip technology for detections of EGFR exon 19 deletions and L858R mutation on both formalin-fixed and paraffin-embedded (FFPE) slides and plasma samples from patients with non-small cell lung cancer (NSCLC). The detection...

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PMID: 22591345
DOI: 10.2174/138920012802138660

Genes

EGFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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