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Tissue and Plasma-Based Highly Sensitive Blocker Displacement Amplicon Nanopore Sequencing for EGFR Mutations in Lung Cancer.

Cancer research and treatment - 1 Apr 2024

Akkhasutthikun Patinya, Kaewsapsak Pornchai, Nimsamer Pattaraporn, Klomkliew Pavit, Visedthorn Suthida, Chanchaem Pragwalai, Teerapakpinyo Chinachote, Payungporn Sunchai, Luangdilok Sutima

Abstract excerpt

PURPOSE: The epidermal growth factor receptor (EGFR) mutation is a widely prevalent oncogene driver in non-small cell lung cancer (NSCLC) in East Asia. The detection of EGFR mutations is a standard biomarker test performed routinely in patients with NSCLC for the selection of targeted therapy. Here, our objective was to develop a portable new technique for detecting EGFR (19Del, T790M, and L858R) mutations based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37986562
DOI: 10.4143/crt.2023.1108
PMCID: PMC11016658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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