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Article

Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2009

Yung Tony K F, Chan K C Allen, Mok Tony S K, Tong Joanna, To Ka-Fai, Lo Y M Dennis

Abstract excerpt

PURPOSE: We aim to develop a digital PCR-based method for the quantitative detection of the two common epidermal growth factor receptor (EGFR) mutations (in-frame deletion at exon 19 and L858R at exon 21) in the plasma and tumor tissues of patients suffering from non-small cell lung cancers. Thes...

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Source

Identifiers

PMID: 19276259
DOI: 10.1158/1078-0432.CCR-08-2622

Genes

EGFR

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19276259-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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