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Article

EGFR mutation detection by microfluidic technology: a validation study.

Journal of clinical pathology - 1 Nov 2013

Malapelle Umberto, Russo Stefania, Pepe Francesco, Sgariglia Roberta, De Luca Caterina, Bellevicine Claudio, Pallante Pierlorenzo, Troncone Giancarlo

Abstract excerpt

Advanced non-small cell lung cancer samples are tested for epidermal growth factor receptor (EGFR) gene mutations. Their detection by direct sequencing is time-consuming. Conversely, the length analysis of fluorescently labelled PCR products is easier. To avoid labelled primers and the automated capillary electrophoresis apparatus, we validated a fast and sensitive chip-based microfluidic technology. The limit of...

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Source

Identifiers

PMID: 23794480
DOI: 10.1136/jclinpath-2013-201730

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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