Case-control studies in the genomic era: a clinician's guide.

doi:10.1016/S1474-4422(06)70524-5

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Article

Case-control studies in the genomic era: a clinician's guide.

The Lancet. Neurology - 1 Aug 2006

Healy Daniel G

Abstract excerpt

The goal of case-control association studies is to find genetic variants in the human genome that influence common traits. The Human Genome and HapMap projects have added fresh impetus to this goal by cataloguing the raw genetic data behind human DNA variation. Studies that associate these genetic variants with phenotype improve both molecular diagnostics and drug discovery and offer clinicians important...

Topics

Case-Control Studies
Chromosome Mapping
Genetic Predisposition to Disease
Genetic Variation
Genetics, Population
Genome, Human
Humans
Linkage Disequilibrium
Phenotype
Publication Bias

Source

Open in PubMed

Identifiers

PMID: 16857576
DOI: 10.1016/S1474-4422(06)70524-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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