Article
What Do We Mean by ‘Replication’ and ‘Validation’ in Genome-Wide Association Studies?
17 Oct 2008
Abstract excerpt
It has been acknowledged that results from genome-wide association studies need to be reproduced in further independent samples. This includes both aspects of replication and validation. Although often used interchangeably, both of these terms have a specific unique meaning and are not synonyms. Based on a number of applications from the literature producing a certain amount of confusion, our aim therefore is to...
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