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Article

Landscapes and archipelagos: spatial organization of gene regulation in vertebrates.

Trends in cell biology - 1 Jul 2012

Montavon Thomas, Duboule Denis

Abstract excerpt

Vertebrate genes controlling critical developmental processes are often regulated by complex sets of global enhancer sequences, located at a distance, within neighboring gene deserts. Recent technological advances have made it possible to investigate the spatial organization of these 'regulatory landscapes'. The integration of such datasets with information on chromatin status, transcriptional activity and...

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PMID: 22560708
DOI: 10.1016/j.tcb.2012.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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