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Article

Orientation, distance, regulation and function of neighbouring genes.

Human genomics - 1 Jan 2009

Gherman Adrian, Wang Ruihua, Avramopoulos Dimitrios

Abstract excerpt

The sequencing of the human genome has allowed us to observe globally and in detail the arrangement of genes along the chromosomes. There are multiple lines of evidence that this arrangement is not random, both in terms of intergenic distances and orientation of neighbouring genes. We have undertaken a systematic evaluation of the spatial distribution and orientation of known genes across the human genome. We...

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Identifiers

PMID: 19164091
DOI: 10.1186/1479-7364-3-2-143
PMCID: PMC2665707

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