Article

Long-range promoter-enhancer contacts are conserved during evolution and contribute to gene expression robustness

2021-02-26

Abstract excerpt

Gene expression is regulated through complex molecular interactions, involving cis -acting elements that can be situated far away from their target genes. Data on long-range contacts between promoters and regulatory elements is rapidly accumulating. However, it remains unclear how these regulatory relationships evolve and how they contribute to the establishment of robust gene expression profiles. Here, we addres...

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Literature Corpus work: ef10ca00-503e-52a2-8a4b-e28e81f72acf
DOI: 10.1101/2021.02.26.432473

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