Article

Human neurodevelopmental genes housed in massive, ancient gene deserts

2026-03-28

Abstract excerpt

Mammalian genomes contain a remarkable proportion of non-coding sequence relative to protein-coding sequence, including megabase-scale gene deserts. The origin of gene deserts and their function have long been mysteries, and most studies probing these questions have focused on specific deserts linked to transcription factors, like SOX9 and MYC. Here, we describe 21 human “lonely genes” located within some of the l...

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Literature Corpus work: 3cae8d69-e3f9-5278-93f2-dee91a6470f0
DOI: 10.64898/2026.03.27.714728

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