Article
Cellular host responses to gliomas.
PloS one - 1 Jan 2012
Najbauer Joseph, Huszthy Peter C, Barish Michael E, Garcia Elizabeth, Metz Marianne Z, Myers Sarah M, Gutova Margarita, Frank Richard T, Miletic Hrvoje, Kendall Stephen E, Glackin Carlotta A, Bjerkvig Rolf, Aboody Karen S
Abstract excerpt
BACKGROUND: Glioblastoma multiforme (GBM) is the most aggressive type of malignant primary brain tumors in adults. Molecular and genetic analysis has advanced our understanding of glioma biology, however mapping the cellular composition of the tumor microenvironment is crucial for understanding the pathology of this dreaded brain cancer. In this study we identified major cell populations attracted by glioma using...
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