Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Animal models to study cancer-initiating cells from glioblastoma.

Frontiers in bioscience (Landmark edition) - 1 Jun 2011

Wee Boyoung, Charles Nikki, Holland Eric C

Abstract excerpt

Three main subtypes of gliomas with distinct molecular pathologies have been modeled in animals to better understand their biology. Genetically engineered mouse models that take advantage of genetic abnormalities observed in human gliomas have been instrumental in this process. These models better recapitulate signaling transduction pathways and the microenvironment that play crucial roles in glioma formation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Gene Transfer Techniques
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Mice, Transgenic

Share to Models, Biological

Share to Neoplastic Stem Cells

Share to Tumor Microenvironment

Source

Identifiers

PMID: 21622174
DOI: 10.2741/3851

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Animal models to study cancer-initiating cells from glioblastoma.PMID 21622174Read ↗

Patient-Derived Glioma Models: From Patients to Dish to AnimalsSemantic proximity Read ↗

From Neural Stem Cells (NSC) to Glioblastoma (GBM): A Natural History of GBM Recapitulated in VitroSemantic proximity Read ↗

From neural stem cells to glioblastoma: A natural history of GBM recapitulated in vitro.Semantic proximity Read ↗

Glioblastoma multiforme: a perspective on recent findings in human cancer and mouse modelsSemantic proximity Read ↗

Advancing Glioblastoma Research with Innovative Brain Organoid-Based ModelsSemantic proximity Read ↗

Next-Generation in vivo Modeling of Human CancersSemantic proximity Read ↗

Mouse Models to Interrogate the Implications of the Differentiation Status in the Ontogeny of GliomasSemantic proximity Read ↗

Glioblastoma stem cells: Molecular characteristics and therapeutic implicationsSemantic proximity Read ↗

Brain stem cells as the cell of origin in gliomaSemantic proximity Read ↗

Heterogeneity of cancer-initiating cells within glioblastomaSemantic proximity Read ↗

Glioblastoma preclinical models: Strengths and weaknessesSemantic proximity Read ↗

A syngeneic glioblastoma mouse model with mesenchymal hallmarks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.