Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Tumor vasculature and glioma stem cells: Contributions to glioma progression.

Cancer letters - 1 Oct 2016

Jhaveri Niyati, Chen Thomas C, Hofman Florence M

Abstract excerpt

Glioblastoma multiforme (GBM), the most malignant of brain tumors, is characterized by extensive vascularization and a high degree of invasion. The current standard of care is not very effective, resulting in tumor recurrence with patients rarely surviving over 2 years. This tumor recurrence is attributed to the presence of chemo and radiation resistant glioma stem cells (GSCs). These cells are associated with...

Topics

Animals
Brain Neoplasms
Cell Transdifferentiation
Disease Progression
Endothelial Cells
Glioma
Humans
Neoplastic Stem Cells
Neovascularization, Pathologic
Paracrine Communication
Pericytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Signal Transduction

Tumor Microenvironment

Source

Identifiers

PMID: 25527451
DOI: 10.1016/j.canlet.2014.12.028

Genes

GSC
HDGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor vasculature and glioma stem cells: Contributions to glioma progression.PMID 25527451Read ↗

Glioma Stem Cells: Signaling, Microenvironment, and TherapySemantic proximity Read ↗

Cancer stem cell-vascular endothelial cell interactions in glioblastoma.Semantic proximity Read ↗

The Impact of the Tumor Microenvironment on the Properties of Glioma Stem-Like CellsSemantic proximity Read ↗

Hypoxia in the glioblastoma microenvironment: shaping the phenotype of cancer stem-like cells.Semantic proximity Read ↗

Vascular Transdifferentiation in the CNS: A Focus on Neural and Glioblastoma Stem‐Like CellsSemantic proximity Read ↗

The Role of Hypoxia and Cancer Stem Cells in Development of GlioblastomaSemantic proximity Read ↗

The perivascular niche microenvironment in brain tumor progressionSemantic proximity Read ↗

Cancer stem cells in glioblastoma—molecular signaling and therapeutic targetingSemantic proximity Read ↗

The progression of gliomas is associated with cancer stem cell phenotype.Semantic proximity Read ↗

Making a tumour's bed: glioblastoma stem cells and the vascular nicheSemantic proximity Read ↗

Glioblastoma stem cells: Molecular characteristics and therapeutic implicationsSemantic proximity Read ↗

The glioblastoma vasculature as a target for cancer therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.