Article
Tumor vasculature and glioma stem cells: Contributions to glioma progression.
Cancer letters - 1 Oct 2016
Jhaveri Niyati, Chen Thomas C, Hofman Florence M
Abstract excerpt
Glioblastoma multiforme (GBM), the most malignant of brain tumors, is characterized by extensive vascularization and a high degree of invasion. The current standard of care is not very effective, resulting in tumor recurrence with patients rarely surviving over 2 years. This tumor recurrence is attributed to the presence of chemo and radiation resistant glioma stem cells (GSCs). These cells are associated with...
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