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Article

Patient-Derived Glioma Models: From Patients to Dish to Animals

30 Sept 2019

Abstract excerpt

Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults associated with a poor survival. Current standard of care consists of surgical resection followed by radiation and chemotherapy. GBMs are highly heterogeneous, having a complex interaction among different cells within the tumor as well as the tumor microenvironment. One of the main challenges in the neuro-oncology field in general,...

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PMID: 31574953
DOI: 10.3390/cells8101177

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