Article
Leveraging information from genetic risk scores of coronary atherosclerosis.
Current opinion in lipidology - 1 Apr 2017
Assimes Themistocles L, Salfati Elias L, Del Gobbo Liana C
Abstract excerpt
PURPOSE OF REVIEW: Genome-wide association studies (GWAS) have identified ∼60 loci for coronary artery disease (CAD). Through genetic risk scores (GRSs), investigators are leveraging this genomic information to gain insights on both the fundamental mechanisms driving these associations as well as their utility in improving risk prediction. RECENT FINDINGS: GRSs of CAD track with the earliest atherosclerosis...
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