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Article

Identification of the Galactose Binding Domain of the Adeno-Associated Virus Serotype 9 Capsid

19 Apr 2012

Abstract excerpt

Adeno-associated virus serotype 9 (AAV9) vectors show promise for gene therapy of a variety of diseases due to their ability to transduce multiple tissues, including heart, skeletal muscle, and the alveolar epithelium of the lung. In addition, AAV9 is unique compared to other AAV serotypes in that it is capable of surpassing the blood-brain barrier and transducing neurons in the brain and spinal cord. It has...

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PMID: 22514350
DOI: 10.1128/jvi.00448-12

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