Article

The infectivity of AAV9 is influenced by the specific location and extent of chemically modified capsid residues

2024-01-15

Abstract excerpt

<title>Abstract</title> <p>Background Several treatments for genetic diseases utilizing recombinant adeno-associated viruses (AAVs) have recently gained approval. However, the development of a greater number of therapeutic AAVs is constrained by certain limitations. While extensive efforts have concentrated on screening AAV genetic libraries, an alternative strategy involves modifying the AAV capsid by attaching...

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Literature Corpus work: 3b141688-993a-5555-bc47-35136cbed52b
DOI: 10.21203/rs.3.rs-3848603/v1

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