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Article

Regulation of NMDA receptor transport: a KIF17-cargo binding/releasing underlies synaptic plasticity and memory in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 18 Apr 2012

Yin Xiling, Feng Xue, Takei Yosuke, Hirokawa Nobutaka

Abstract excerpt

Regulation of NMDA receptor trafficking is crucial to modulate neuronal communication. Ca(2+)/calmodulin-dependent protein kinase phosphorylates the tail domain of KIF17, a member of the kinesin superfamily, to control NMDA receptor subunit 2B (GluN2B) transport by changing the KIF17-cargo interaction in vitro. However, the mechanisms of regulation of GluN2B transport in vivo and its physiological significance...

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Source

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Identifiers

PMID: 22514311
DOI: 10.1523/JNEUROSCI.0718-12.2012
PMCID: PMC6703487

Genes

KIF17

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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