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Article

Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Aug 2008

Sandoz Guillaume, Tardy Magalie P, Thümmler Susanne, Feliciangeli Sylvain, Lazdunski Michel, Lesage Florian

Abstract excerpt

Twik-related K+ (TREK) channels produce background currents that regulate cell excitability. In vivo, TREK-1 is involved in neuronal processes including neuroprotection against ischemia, general anesthesia, pain perception, and mood. Recently, we demonstrated that A-kinase anchoring protein AKAP150 binds to a major regulatory domain of TREK-1, promoting drastic changes in channel regulation by polyunsaturated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18716213
DOI: 10.1523/JNEUROSCI.1962-08.2008
PMCID: PMC6671063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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