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Article

A decrease in protein level and a missense polymorphism of KIF17 are associated with schizophrenia.

Psychiatry research - 15 Dec 2015

Ratta-Apha Woraphat, Mouri Kentaro, Boku Shuken, Ishiguro Hiroki, Okazaki Satoshi, Otsuka Ikuo, Sora Ichiro, Arinami Tadao, Shirakawa Osamu, Hishimoto Akitoyo

Abstract excerpt

It has been shown that the dysfunction of N-methyl-d-asparate (NMDA) receptors-mediated neurotransmission plays a role in the pathophysiology of schizophrenia. Especially, GluN2B, a subunit of NMDA receptors, associated trafficking complex is altered in the prefrontal cortex of schizophrenia. The kinesin superfamily motor protein 17 (KIF17) is known as a transporter of NR2B.Previous studies showed that a...

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Source

Identifiers

PMID: 26421900
DOI: 10.1016/j.psychres.2015.09.031

Genes

KIF17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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