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Article

Genetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implications.

PloS one - 1 Jan 2012

Wolen Aaron R, Phillips Charles A, Langston Michael A, Putman Alex H, Vorster Paul J, Bruce Nathan A, York Timothy P, Williams Robert W, Miles Michael F

Abstract excerpt

BACKGROUND: Individual differences in initial sensitivity to ethanol are strongly related to the heritable risk of alcoholism in humans. To elucidate key molecular networks that modulate ethanol sensitivity we performed the first systems genetics analysis of ethanol-responsive gene expression in brain regions of the mesocorticolimbic reward circuit (prefrontal cortex, nucleus accumbens, and ventral midbrain)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22511924
DOI: 10.1371/journal.pone.0033575
PMCID: PMC3325236

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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