Article
Integrative Analysis of Genetic, Genomic, and Phenotypic Data for Ethanol Behaviors: A Network-Based Pipeline for Identifying Mechanisms and Potential Drug Targets.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Bogenpohl James W, Mignogna Kristin M, Smith Maren L, Miles Michael F
Abstract excerpt
Complex behavioral traits, such as alcohol abuse, are caused by an interplay of genetic and environmental factors, producing deleterious functional adaptations in the central nervous system. The long-term behavioral consequences of such changes are of substantial cost to both the individual and society. Substantial progress has been made in the last two decades in understanding elements of brain mechanisms...
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