Article
The sequenced rat brain transcriptome--its use in identifying networks predisposing alcohol consumption.
The FEBS journal - 1 Sept 2015
Saba Laura M, Flink Stephen C, Vanderlinden Lauren A, Israel Yedy, Tampier Lutske, Colombo Giancarlo, Kiianmaa Kalervo, Bell Richard L, Printz Morton P, Flodman Pamela, Koob George, Richardson Heather N, Lombardo Joseph, Hoffman Paula L, Tabakoff Boris
Abstract excerpt
UNLABELLED: A quantitative genetic approach, which involves correlation of transcriptional networks with the phenotype in a recombinant inbred (RI) population and in selectively bred lines of rats, and determination of coinciding quantitative trait loci for gene expression and the trait of interest, has been applied in the present study. In this analysis, a novel approach was used that combined DNA-Seq data, data...
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