Article

GSK3B inhibition partially reverses brain ethanol-induced transcriptomic changes in C57BL/6J mice: Expression network co-analysis with human genome-wide association studies

2025-04-06

Abstract excerpt

Alcohol use disorder (AUD) is a chronic behavioral disease with greater than 50% of its risk due to complex genetic contributions. Existing pharmacological and behavioral treatments for AUD are minimally effective and underutilized. Animal model behavioral genetics and human genome-wide association studies have begun to identify individual genes contributing to the progressive compulsive consumption of ethanol tha...

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Literature Corpus work: e6d5c0a4-0ba7-5393-8a8e-d7e0cce956e6
DOI: 10.1101/2025.04.03.647116

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