Article

Gene network inference and master regulator analysis identifies the estrogen-related receptor gamma (ERRγ) as a therapeutic target for alcohol use disorder (AUD)

2025-11-16

Abstract excerpt

Differential gene expression is often inadequate to predict the activity of transcription factors and their contribution to the phenotypes associated with specific gene expression states. Here we used a systems biology approach based on gene network inference and master regulator analysis (MRA) to identify candidate drivers of the gene network dysregulations in the prefrontal cortex (PFC) of human subjects with a...

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Literature Corpus work: f15b202d-a019-5e01-8b2c-01712110cf91
DOI: 10.1101/2025.11.15.688629

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Gene network inference and master regulator analysis identifies the estrogen-related receptor gamma (ERRγ) as a therapeutic target for alcohol use disorder (AUD)DOI 10.1101/2025.11.15.688629Read

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