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Article

17q allele loss is associated with lymph node metastasis in locally aggressive human colorectal cancer.

The Journal of pathology - 1 Mar 1995

Purdie C A, Piris J, Bird C C, Wyllie A H

Abstract excerpt

A consecutive series of 87 colorectal tumours were studied for loss of a polymorphic probe on chromosome 17q and of the 64 informative cases, 13 (20 per cent) showed loss of heterozygosity (LOH). Examples of LOH were found in carcinomas of all stages and in a large non-invasive adenoma. There was...

Topics

Adenoma
Aged
Alleles
Carcinoma
Chromosome Deletion
Chromosomes, Human, Pair 17
Colorectal Neoplasms
Female
Flow Cytometry
Heterozygote
Humans
Lymphatic Metastasis
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Polymorphism, Restriction Fragment Length

Survival Rate

Source

Identifiers

PMID: 7745498
DOI: 10.1002/path.1711750307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7745498-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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