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Article

On optimal gene-based analysis of genome scans.

Genetic epidemiology - 1 May 2012

Bacanu Silviu-Alin

Abstract excerpt

Univariate analysis of markers has modest power when there are multiple causal variants within a gene. Under this scenario, combining the effects of all variants from a gene in a gene-wide statistic is thought to increase power. However, it is not really clear (1) what is the performance of most commonly used gene-wide methods for whole genome scans and (2) how scalable these methods are for more computationally...

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PMID: 22508187
DOI: 10.1002/gepi.21625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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