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Article

Joint rare variant association test of the average and individual effects for sequencing studies.

PloS one - 1 Jan 2012

Wang Yuanjia, Chen Yin-Hsiu, Yang Qiong

Abstract excerpt

For many complex traits, single nucleotide polymorphisms (SNPs) identified from genome-wide association studies (GWAS) only explain a small percentage of heritability. Next generation sequencing technology makes it possible to explore unexplained heritability by identifying rare variants (RVs). Existing tests designed for RVs look for optimal strategies to combine information across multiple variants. Many of the...

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PMID: 22468164
DOI: 10.1371/journal.pone.0032485
PMCID: PMC3309869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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