MGAS: a powerful tool for multivariate gene-based genome-wide association analysis.

Abstract excerpt

MOTIVATION: Standard genome-wide association studies, testing the association between one phenotype and a large number of single nucleotide polymorphisms (SNPs), are limited in two ways: (i) traits are often multivariate, and analysis of composite scores entails loss in statistical power and (ii) gene-based analyses may be preferred, e.g. to decrease the multiple testing problem. RESULTS: Here we present a new...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genome, Human
• Share to Genome-Wide Association Study