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Article

Gene set analysis of SNP data: benefits, challenges, and future directions.

European journal of human genetics : EJHG - 1 Aug 2011

Fridley Brooke L, Biernacka Joanna M

Abstract excerpt

The last decade of human genetic research witnessed the completion of hundreds of genome-wide association studies (GWASs). However, the genetic variants discovered through these efforts account for only a small proportion of the heritability of complex traits. One explanation for the missing heritability is that the common analysis approach, assessing the effect of each single-nucleotide polymorphism (SNP)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21487444
DOI: 10.1038/ejhg.2011.57
PMCID: PMC3172936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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