Effects of Amerindian Genetic Ancestry on Clinical Variables and Therapy in Patients with Rheumatoid Arthritis.

doi:10.3899/jrheum.160485

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Article

Effects of Amerindian Genetic Ancestry on Clinical Variables and Therapy in Patients with Rheumatoid Arthritis.

The Journal of rheumatology - 1 Dec 2017

Sánchez Elena, García de la Torre Ignacio, Sacnún Mónica, Goñi Mario, Berbotto Guillermo, Paira Sergio, Musuruana Jorge Luis, Graf César, Alvarellos Alejandro, Messina Osvaldo D, Babini Alejandra, Strusberg Ingrid, Marcos Juan Carlos, Scherbarth Hugo, Spindler Alberto, Quinteros Ana, Toloza Sergio, Moreno José Luis C, Catoggio Luis J, Tate Guillermo, Eimon Alicia, Citera Gustavo, Pellet Antonio Catalán, Nasswetter Gustavo, Cardiel Mario H, Miranda Pedro, Ballesteros Francisco, Esquivel-Valerio Jorge A, Maradiaga-Ceceña Marco A, Acevedo-Vásquez Eduardo M, García Conrado García, Tusié-Luna Teresa, Pons-Estel Bernardo A, Alarcón-Riquelme Marta E

Abstract excerpt

OBJECTIVE: To define whether Amerindian genetic ancestry correlates with clinical and therapeutic variables in admixed individuals with rheumatoid arthritis (RA) from Latin America. METHODS: Patients with RA (n = 1347) and healthy controls (n = 1012) from Argentina, Mexico, Chile, and Peru were included. Samples were genotyped for the Immunochip v1 using the Illumina platform. Clinical data were obtained through...

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PMID: 29093158
DOI: 10.3899/jrheum.160485

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