Article
Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.
Arthritis and rheumatism - 1 Dec 2010
Sanchez Elena, Webb Ryan D, Rasmussen Astrid, Kelly Jennifer A, Riba Laura, Kaufman Kenneth M, Garcia-de la Torre Ignacio, Moctezuma Jose F, Maradiaga-Ceceña Marco A, Cardiel-Rios Mario H, Acevedo Eduardo, Cucho-Venegas Mariano, Garcia Mercedes A, Gamron Susana, Pons-Estel Bernardo A, Vasconcelos Carlos, Martin Javier, Tusié-Luna Teresa, Harley John B, Richardson Bruce, Sawalha Amr H, Alarcón-Riquelme Marta E
Abstract excerpt
OBJECTIVE: To assess whether genetically determined Amerindian ancestry predicts increased presence of risk alleles of known susceptibility genes for systemic lupus erythematosus (SLE). METHODS: Single-nucleotide polymorphisms (SNPs) within 16 confirmed genetic susceptibility loci for SLE were ge...
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